Consolidate your supply chain with our benchmark botanical extracts, therapeutic cold-pressed lipid carriers, and pure standardized polyphenols, all backed by batch-specific chromatographic validation and comprehensive regulatory documentation.
Quercetin Dihydrate (2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one dihydrate, CAS: 6151-25-2) represents the gold standard in crystalline bioflavonoids. Sourced primarily via selective acidic hydrolysis of rutin extracted from the flower buds of Sophora japonica L. (Japanese pagoda tree), this active ingredient requires rigorous crystallographic control to achieve therapeutic stability.
Quercetin dihydrate contains approximately 10.5% to 12.0% stoichiometric crystal water within its lattice matrix. In industrial scale-up, controlling this bound hydration is vital: premature dehydration due to excessive drying heat converts the material into hygroscopic amorphous anhydrous quercetin, impacting shelf stability and compressibility.
International buyers often encounter assay disputes due to divergent testing methods. While legacy UV spectrophotometric testing frequently records values >98.0% by capturing overlapping flavone absorbance bands, our QA testing uses validated reverse-phase HPLC (USP/EP monographs) to separate pure quercetin from related flavonoids like kaempferol and isorhamnetin.
Native quercetin crystals are hydrophobic with low gastrointestinal dissolution rates. As a premier OEM/ODM exporter, we utilize air-classifier jet milling to supply ultra-fine micronized grades (D50 < 5μm, D90 < 15μm, 80 to 200 mesh) that drastically improve direct-compression flowability and functional absorption in aqueous matrices.
| Analytical Parameter | USP Standard Specification | European Pharmacopoeia (EP) | SV Botanica Export Grade |
|---|---|---|---|
| Assay Identification (HPLC) | 95.0% – 102.0% (Anhydrous basis) | 95.0% – 101.0% (Dried substance) | ≥ 98.0% (HPLC Certified) |
| Loss on Drying (Water Content) | 9.5% – 12.5% | 10.0% – 12.0% | 10.5% – 11.8% (Strict Dihydrate) |
| Heavy Metals (ICP-MS) | NMT 10 ppm (Pb ≤ 0.5, As ≤ 1.0) | Complies with Reg (EU) 2023/915 | Pb ≤ 0.2ppm, Cd ≤ 0.1ppm, Hg ≤ 0.05ppm |
| Pesticide Multi-Residue | USP <561> Compliant | Regulation (EC) No 396/2005 | Full EU MRL Clean Scan |
| Ethylene Oxide (ETO) | Undetected (< 0.1 mg/kg) | Reg (EU) 2019/1793 (< 0.02 mg/kg) | 0.00% Zero-ETO Ionization Sterilized |
| Bulk Density | 0.30 g/ml – 0.55 g/ml | Specified on Certificate | Custom (0.35 g/ml loose / 0.65 g/ml tapped) |
Global sourcing teams are moving beyond basic compliance. Demand for quercetin is accelerating across longevity therapeutics, immunomodulation formulations, and functional nutrition. Procurement leaders must evaluate several major shifts taking place across the international supply chain.
Clinical research highlighting quercetin as a potent senolytic agent—capable of clearing damaged senescent cells—has shifted procurement from standard immune support to premium healthy-aging products. Demand is surging for custom pre-blends combining Quercetin Dihydrate with Fisetin, Trans-Resveratrol, Spermidine, and Bromelain (which enhances intestinal uptake).
Standard crystalline quercetin exhibits low human bioavailability (under 2%). Forward-thinking brands are switching from traditional raw powders to enhanced delivery mechanisms. We have engineered specialized OEM processing lines to support these advanced formats:
EU Rapid Alert System for Food and Feed (RASFF) notifications have made cross-contamination a top procurement risk. Global regulators now actively reject botanical consignments containing trace 2-chloroethanol or unapproved extraction solvent residues (such as methanol or acetone).
Under the EU Corporate Sustainability Due Diligence Directive (CSDDD) and US SEC ESG transparency guidelines, multinational brands must now verify raw material origin back to specific agrarian cultivation clusters. Our contract harvesting operations guarantee complete farm-to-shipping traceability.
From raw API powder supply to shelf-ready packaged goods, our GMP-certified contract manufacturing services help global nutraceutical brands launch market-ready formulations faster and with lower overhead.
State-of-the-art automatic capsule filling machinery operating within Class 100,000 cleanrooms. We provide size #00, #0, and #1 capsules in both vegetarian (HPMC/Pullulan) and bovine gelatin formats, formulated with clean-label excipients (such as organic rice hull concentrate instead of magnesium stearate or silicon dioxide).
Native quercetin powder suffers from poor cohesion and dies easily on high-speed tablet presses. Our proprietary wet and fluid-bed granulation lines transform fine crystalline powder into free-flowing, high-density granules tailored for rapid tableting, chewable wafers, and effervescent delivery systems.
Customized packaging options engineered for long ocean freight and tropical customs storage. We supply 25kg tamper-evident UN-certified fiber drums with heat-sealed food-grade double polyethylene inner liners, nitrogen-flushed light-barrier aluminum bags (1kg to 5kg), and retail-ready finished bottles with multi-lingual regulatory compliance labels.
Importing raw botanical ingredients into regulated markets requires air-tight documentation. We treat regulatory paperwork with the exact same rigor as physical manufacturing, ensuring seamless clearance through customs and FDA/EFSA audits.
Every shipment includes an authenticated Certificate of Analysis (CoA) with stated test methods, Technical Data Sheet (TDS), Safety Data Sheet (SDS/MSDS per GHS), Process Flow Chart, Allergen Statements, and BSE/TSE-Free declarations ready for internal audit.
We proactively support US importers' Foreign Supplier Verification Programs (FSVP) and furnish European buyers with comprehensive pesticide panels audited by independent ISO/IEC 17025 accredited testing laboratories like Eurofins and SGS.
Avoid project delays. Our technical team dispatches pre-shipment evaluation samples (100g to 500g) alongside authentic batch-specific chromatography within 24 business hours via expedited DHL/FedEx courier services.
Key technical and regulatory answers prepared by our quality assurance and logistics experts to streamline your vendor audit process.
Direct factory communication. Request a formal price quote, reserve stock from upcoming extraction lots, or order a certified 100g pre-shipment evaluation sample with complete batch analytical data.
